Sanitizable Mattress Protectors

Sanitizable Mattress Protectors offer a practical way to explore mattress protection options for bedrooms, guest spaces and professional care settings. Shop a selection of sizes and styles at Mattress Firm to find a mattress protector that fits your sleep setup and everyday needs.

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Sleepy's Signature TOTAL DEFENSE Mattress Protector

5687

Starting at

$99⁹⁹

Temperature
Allergies

Save $100 when you bundle¹⁰.

Sleepy's Deluxe Comfort Cool Mattress Protector

4179

Starting at

$129⁹⁹

Temperature
Allergies

Save $150 when you bundle¹⁰.

Tempur-Pedic TEMPUR-Protect Breeze Mattress Protector

802

Starting at

$259⁰⁰

Sleepy's Signature Total Encasement Mattress Protector

1001

Starting at

$129⁹⁹

Temperature

Bedgear Dri-Tec Mattress Protector

150

Starting at

$119⁹⁹

Temperature
Allergies

Allerease Maximum Mattress Protector

237

Starting at

$41⁶⁴

Temperature
Allergies

Allerease Ultimate Mattress Protector

337

Starting at

$34⁹⁹

Temperature
Allergies

Sleepy's Basics Waterproof Mattress Protector

2492

Starting at

$29⁹⁹

Temperature
Allergies

Save $50 when you bundle¹⁰.

Sleepy's 3" Gel Memory Foam Mattress Topper

396

Starting at

$94⁹⁹

$139⁹⁹

$45 OFF

Medium Comfort,

Temperature

Bedgear Ver-Tex Performance Mattress Protector

162

Starting at

$259⁹⁹

Temperature

Bedgear StretchWick Mattress Protector

155

Starting at

$89⁹⁹

Temperature
Allergies

Sleepy's 4" Reversible Gel Memory Foam Topper

Starting at

$134⁰⁰

$199⁹⁹

$66 OFF

Medium Comfort,

Temperature
Allergies

Tempur-Pedic TEMPUR-AdaptMattress Topper

8510

Starting at

$189⁰⁰

$269⁰⁰

$80 OFF

Medium Comfort,

Temperature
Allergies

Tempur-Pedic TEMPUR-Adapt + Cooling Mattress Topper

4642

Starting at

$389⁰⁰

Medium Comfort,

Temperature
Allergies

Purple RestorePlus Cool Touch 13" Hybrid Mattress

997

Starting at

$3240⁰⁰

$3899⁰⁰

$659 OFF

Medium Comfort, best for

Back, Side, Stomach Sleepers
Pain
Allergies
Bed Partner
Toss and Turn

$300 ^◇ adjustable base instant gift with purchase.

Purple Restore Cool Touch 11.5" Hybrid Mattress

782

Starting at

$3000⁰⁰

$3699⁰⁰

$699 OFF

Medium Comfort, best for

Back, Side, Stomach Sleepers
Pain
Bed Partner
Temperature
Toss and Turn

$300 ^◇ adjustable base instant gift with purchase.

Sanitizable mattress protectors help create a cleaner, more comfortable sleep environment by adding a protective layer between your mattress and everyday spills, sweat, skin oils, dust and allergens. Designed for regular cleaning, these mattress covers may feature machine-washable fabrics, waterproof barriers and durable construction that help protect the mattress while preserving its comfort and feel. Look for a washable mattress protector made with breathable materials that fit securely over your mattress without bunching or making excess noise. A quality waterproof mattress protector can also help guard against accidental spills and stains, making it a practical choice for children’s beds, guest rooms, dorm rooms and households looking for an easier mattress care routine. Care instructions vary by product, so always review the manufacturer’s label before washing or sanitizing a mattress protector. Many washable mattress protectors can be laundered in a household washing machine using the recommended water temperature and a mild detergent, while some require specific drying settings to help maintain the waterproof backing and shape. Avoid bleach, fabric softener or high heat unless the care label specifically allows them, since these products and settings may damage protective materials. A properly maintained sanitizable mattress protector can help extend the useful life of your mattress, support a fresher sleep space and make routine bedroom cleaning more convenient without changing the feel of your bed.

What is a sanitizable mattress protector? + -

A sanitizable mattress protector is designed for routine cleaning and sanitizing according to the care instructions. It creates a washable layer between your mattress and everyday spills, moisture and household messes.

How do you clean a sanitizable mattress protector? + -

Follow the protector’s care label for washing, drying and approved cleaning products. Use the recommended water temperature and cycle, then dry it as directed to help maintain its materials and construction.

What materials are used in sanitizable mattress protectors? + -

Sanitizable mattress protectors may feature cotton, polyester, polyurethane or blended fabrics. Each material offers a different feel, texture and care routine, so check the product details before choosing one.

Can a sanitizable mattress protector be used with any mattress? + -

Sanitizable mattress protectors are made for use over mattresses and may come in different designs, including fitted and zippered styles. Check the product description to confirm the protector’s intended mattress compatibility.

How often should you clean a sanitizable mattress protector? + -

Clean your mattress protector as needed based on household use, spills and personal preferences. Regular laundering can help keep the sleep surface feeling fresh while following the care label helps preserve the protector.