Stain Resistant Mattress Protectors

Find Stain Resistant Mattress Protectors at Mattress Firm to help you shop for mattress protection that fits your sleep setup, preferences and budget. Explore available sizes and styles to find the right match for your mattress and create a more comfortable bedroom.

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Sleepy's Signature TOTAL DEFENSE Mattress Protector

5687

Starting at

$99⁹⁹

Temperature
Allergies

Save $100 when you bundle¹⁰.

Sleepy's Basics Waterproof Mattress Protector

2492

Starting at

$49⁹⁹

Temperature
Allergies

Save $50 when you bundle¹⁰.

Allerease Ultimate Mattress Protector

337

Starting at

$49⁹⁹

Temperature
Allergies

Bedgear Ver-Tex Performance Mattress Protector

162

Starting at

$259⁹⁹

Temperature

Sleepy's Deluxe Comfort Cool Mattress Protector

4179

Starting at

$189⁹⁹

Temperature
Allergies

Save $150 when you bundle¹⁰.

Tempur-Pedic TEMPUR-Protect Breeze Mattress Protector

802

Starting at

$259⁰⁰

Sleepy's Signature Total Encasement Mattress Protector

1001

Starting at

$159⁹⁹

Temperature

Bedgear Dri-Tec Mattress Protector

150

Starting at

$209⁹⁹

Temperature
Allergies

Allerease Maximum Mattress Protector

237

Starting at

$30⁶⁴

Temperature
Allergies

Bedgear StretchWick Mattress Protector

155

Starting at

$129⁹⁹

Temperature
Allergies

Sealy Ellenton II 12" Medium Mattress

Starting at

$749⁰⁰

$1049⁰⁰

$300 OFF

Medium Comfort, best for

Back, Side, Stomach Sleepers
Pain
Allergies

FREE ADJUSTABLE BASE ³ with code ELEVATE

Sealy Ellenton II 12" Firm Mattress

Starting at

$1519⁰⁰

Firm Comfort, best for

Back Sleepers
Pain
Allergies

FREE ADJUSTABLE BASE ³ with code ELEVATE

A stain resistant mattress protector helps defend your mattress from everyday spills, sweat, body oils, food stains and other messes that can affect its appearance and freshness. Designed to create a protective layer between your sheets and mattress, a quality mattress protector can help keep moisture and stains from reaching the mattress surface while supporting a cleaner, more comfortable sleep environment. Look for a breathable mattress protector with a soft, quiet feel that fits securely over your mattress without changing the comfort of your bed. Options with elastic edges or a fitted-sheet design can provide a snug fit, while a waterproof mattress protector offers additional protection against liquid spills, accidents and nighttime moisture. Adding a stain resistant mattress cover to your bedding routine can also make mattress care easier and help protect your investment over time. Wash the protector regularly according to the care instructions, especially after spills or illness, and choose a machine-washable option for convenient upkeep. Before shopping, confirm the mattress protector’s size and pocket depth so it fits your twin, Twin XL, full, queen, king or California King mattress properly. With the right combination of stain protection, breathability, comfortable materials and a secure fit, a mattress protector can help your bed stay fresher and more inviting night after night.

What is a stain resistant mattress protector? + -

A stain resistant mattress protector is a removable bedding layer designed to cover the mattress surface and help simplify cleanup from everyday spills and messes. It typically fits over the mattress like a fitted sheet.

What materials are used in stain resistant mattress protectors? + -

Stain resistant mattress protectors may feature materials such as cotton, polyester, rayon or blended fabrics. Some include a soft quilted surface or a protective backing for added coverage.

How should I care for a stain resistant mattress protector? + -

Follow the care instructions on the product label. Many protectors can be machine washed and dried on a low setting. Avoid harsh cleaners unless the care instructions specifically recommend them.

Will a stain resistant mattress protector change how my mattress feels? + -

The feel can vary by design. Quilted protectors may add a light layer of cushioning, while streamlined options are designed to sit smoothly beneath your sheets.

How does a stain resistant mattress protector fit into a bedding setup? + -

Place the protector directly over the mattress and beneath the fitted sheet. This creates a removable layer between the mattress and your everyday bedding.