Mattresses With Antibacterial Cover

Find the right fit for restful nights with Mattresses With Antibacterial Cover. Explore a range of mattress sizes, feels and comfort options to help you create a sleep space that suits your needs and supports better zzz's.

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Sleepy's Signature TOTAL DEFENSE Mattress Protector

5735

Starting at

$99⁹⁹

Temperature
Allergies

Save $100 when you bundle¹⁰.

Sleepy's Deluxe Comfort Cool Mattress Protector

4229

Starting at

$189⁹⁹

Temperature
Allergies

Save $150 when you bundle¹⁰.

Sleepy's Signature Total Encasement Mattress Protector

1004

Starting at

$159⁹⁹

Temperature

Beautyrest Silver BRS900 11.75" Extra Firm Mattress

3302

Starting at

$709⁹⁹

$1699⁹⁹

$990 OFF

Extra Firm Comfort, best for

Back, Stomach Sleepers
Temperature
Pain
Allergies
Bed Partner
Toss and Turn

FREE ADJUSTABLE BASE ³ with code ELEVATE

Beautyrest BR800 11.25" Firm Mattress

2239

Starting at

$619⁹⁹

$1299⁹⁹

$680 OFF

Firm Comfort, best for

Back, Stomach Sleepers
Toss and Turn
Pain
Bed Partner
Temperature

FREE ADJUSTABLE BASE ³ with code ELEVATE

Sleepy's 3" Gel Memory Foam Mattress Topper

398

Starting at

$139⁹⁹

Medium Comfort,

Temperature

Tulo Bamboo 10" Medium Green Tea Memory Foam Mattress

5567

Starting at

$379⁹⁹

$889⁹⁹

$510 OFF

Medium Comfort, best for

Back, Side, Stomach Sleepers
Pain
Bed Partner
Temperature
Allergies
Toss and Turn

Tulo Bamboo 12" Medium Plush Green Tea Memory Foam Mattress

5567

Starting at

$329⁹⁹

$789⁹⁹

$460 OFF

Medium Comfort, best for

Back, Side, Stomach Sleepers
Bed Partner
Pain
Temperature
Toss and Turn

Beautyrest BR800 13.5" Medium Pillow Top Mattress

1868

Starting at

$819⁹⁹

$1499⁹⁹

$680 OFF

Medium Comfort, best for

Back, Side, Stomach Sleepers
Toss and Turn
Pain
Bed Partner
Temperature

FREE ADJUSTABLE BASE ³ with code ELEVATE

Beautyrest Silver BRS900-C 13.75" Extra Firm Mattress

1816

Starting at

$859⁹⁹

$1999⁹⁹

$1140 OFF

Extra Firm Comfort, best for

Back, Stomach Sleepers
Temperature
Pain
Bed Partner
Toss and Turn

FREE ADJUSTABLE BASE ³ with code ELEVATE

Tulo Bamboo 8" Medium Green Tea Memory Foam Mattress

5567

Starting at

$249⁹⁹

$609⁹⁹

$360 OFF

Medium Comfort, best for

Back, Side, Stomach Sleepers
Pain
Bed Partner
Temperature
Toss and Turn

Beautyrest Silver BRS900 11.75" Medium Firm Mattress

1749

Starting at

$659⁹⁹

$899⁹⁹

$240 OFF

Medium Comfort, best for

Back, Side, Stomach Sleepers
Allergies
Bed Partner
Temperature
Pain
Toss and Turn

FREE ADJUSTABLE BASE ³ with code ELEVATE

Beautyrest BR800 12" Plush Euro Top Mattress

739

Starting at

$569⁹⁹

$1399⁹⁹

$830 OFF

Plush Comfort, best for

Side Sleepers
Toss and Turn
Pain
Bed Partner
Temperature

Beautyrest Silver BRS900 12" Plush Mattress

1147

Starting at

$729⁹⁹

$1699⁹⁹

$970 OFF

Plush Comfort, best for

Side Sleepers
Temperature
Pain
Bed Partner
Toss and Turn

FREE ADJUSTABLE BASE ³ with code ELEVATE

Allerease Ultimate Mattress Protector

337

Starting at

$49⁹⁹

Temperature
Allergies

Sleepy's 4" Reversible Gel Memory Foam Topper

Starting at

$169⁹⁹

$249⁹⁹

$80 OFF

Medium Comfort,

Temperature
Allergies

Purple RestorePlus 13" Soft Hybrid Mattress

3534

Starting at

$2860⁰⁰

$3499⁰⁰

$639 OFF

Plush Comfort, best for

Side Sleepers
Pain
Allergies
Bed Partner
Toss and Turn
Temperature

Purple RestorePlus 13" Firm Hybrid Mattress

1667

Starting at

$2860⁰⁰

$3499⁰⁰

$639 OFF

Firm Comfort, best for

Back, Stomach Sleepers
Pain
Allergies
Bed Partner
Toss and Turn
Temperature

Purple Restore 11.5" Soft Hybrid Mattress

1666

Starting at

$1830⁰⁰

$2299⁰⁰

$469 OFF

Plush Comfort, best for

Side Sleepers
Pain
Allergies
Bed Partner
Toss and Turn
Temperature

Purple RestorePlus Cool Touch 13" Hybrid Mattress

1005

Starting at

$3160⁰⁰

$3799⁰⁰

$639 OFF

Medium Comfort, best for

Back, Side, Stomach Sleepers
Pain
Allergies
Bed Partner
Toss and Turn

$300 ^◇ adjustable base instant gift with purchase.

Purple RestorePremier Cool Touch 13" Hybrid Mattress

856

Starting at

$3510⁰⁰

$4099⁰⁰

$589 OFF

Medium Comfort, best for

Back, Side, Stomach Sleepers
Pain
Allergies
Bed Partner
Toss and Turn

$300 ^◇ adjustable base instant gift with purchase.

Beautyrest Silver BRS900-C 14.5" Medium Mattress

795

Starting at

$599⁹⁹

$1399⁹⁹

$800 OFF

Medium Comfort, best for

Back, Side, Stomach Sleepers
Temperature
Pain
Bed Partner
Toss and Turn

FREE ADJUSTABLE BASE ³ with code ELEVATE

Purple Restore Cool Touch 11.5" Hybrid Mattress

790

Starting at

$3000⁰⁰

$3699⁰⁰

$699 OFF

Medium Comfort, best for

Back, Side, Stomach Sleepers
Pain
Bed Partner
Temperature
Toss and Turn

$300 ^◇ adjustable base instant gift with purchase.

Beautyrest BR800 Greenwood 10.5" Firm Mattress

3405

Starting at

$1299⁹⁹

Firm Comfort, best for

Back, Stomach Sleepers
Bed Partner
Toss and Turn
Temperature
Pain

FREE ADJUSTABLE BASE ³ with code ELEVATE

Beautyrest BR800 11.5" Medium Firm Mattress

3152

Starting at

$459⁹⁹

$999⁹⁹

$540 OFF

Medium Comfort, best for

Back, Side, Stomach Sleepers
Toss and Turn
Pain
Bed Partner
Temperature

Purple Restore 11.5" Firm Hybrid Mattress

843

Starting at

$2700⁰⁰

$3399⁰⁰

$699 OFF

Firm Comfort, best for

Back, Stomach Sleepers
Pain
Allergies
Bed Partner
Toss and Turn
Temperature

Mattresses with antibacterial covers are designed to help create a cleaner, more comfortable sleep environment by using cover fabrics treated to inhibit the growth of certain bacteria on the mattress surface. This feature can be especially appealing for shoppers looking for a mattress with a hygienic cover, antimicrobial mattress materials or added protection against everyday buildup from sweat, body oils and moisture. Antibacterial mattress covers are available across a variety of mattress types, including memory foam, hybrid, innerspring and TEMPUR-Material™ mattresses, so you can choose the comfort level and support system that best suits your sleep style. Look for a breathable mattress cover with moisture-wicking properties to help promote airflow and temperature regulation, while also checking the product details to understand whether the cover is removable, machine washable or intended to be used with a separate mattress protector. An antibacterial cover can be a useful part of a complete mattress-cleaning routine, but it does not replace regular care or guarantee that a mattress is free from germs, allergens or dust mites. Use a properly fitted, washable mattress protector for an additional layer between your sheets and mattress, wash bedding according to the manufacturer’s instructions and allow moisture to dry fully before making the bed. It is also important to review the mattress warranty and care instructions before removing or washing any cover, since some mattress covers are not designed to be taken off. By pairing a mattress with an antibacterial cover and breathable bedding with good sleep habits, you can help maintain a fresher-feeling sleep surface and get better zzz's for less.

What is an antibacterial mattress cover made of? + -

Antibacterial mattress covers may be made from materials such as cotton, polyester, rayon or blended fabrics, with a specialized treatment incorporated into the cover.

Do antibacterial mattress covers change how a mattress feels? + -

The feel depends on the cover’s fabric, quilting and construction. Look for breathable, soft-touch or quilted materials based on your comfort preferences.

Can I use sheets with a mattress that has an antibacterial cover? + -

Yes. Fitted sheets are designed to be used over mattress covers. Choose sheets with a pocket depth that accommodates your mattress and any additional topper.

How should I care for an antibacterial mattress cover? + -

Care instructions vary by cover, so review the manufacturer’s label before washing or spot cleaning. Use the recommended water temperature, detergent and drying method.

Can an antibacterial mattress cover be added to any mattress? + -

Many mattress covers are designed to fit standard mattresses, but construction and depth can vary. Check the cover’s fit specifications and your mattress dimensions before choosing one.